Effects of aging on quantitative MRI values in the human subcortex.
Dr Max C Keuken, University of Amsterdam, the Netherlands
WHEN: Thursday 25 February, 1:30-2:30pm
WHERE: Keats Reading Room (AVG17)
The aging brain undergoes several anatomical changes that can be measured with Magnetic Resonance Imaging (MRI). Early studies using lower field strengths have assessed changes in tissue properties mainly qualitatively, using T1- or T2*- weighted images to provide image contrast. With the development of higher field strengths (7 Tesla and above) and more advanced MRI contrasts, quantitative measures can be acquired even of small subcortical structures. In this talk I will present some of the volumetric, spatial, and quantitative MRI parameter changes associated with healthy aging in a range of subcortical nuclei, including the basal ganglia, red nucleus and, the periaqueductal grey.
Dr Max C. Keuken is currently a post-doctoral researcher in the Faculty of Social and Behavioural Sciences, University of Amsterdam. Max completed his Ph.D in 2015 at the University of Amsterdam, NL, under the supervision of Birte U. Forstmann and Robert Turner. His main research interest is the role of subcortical nuclei in decision-making using ultra-high field structural and functional MRI. Despite being less than 1yr post-PhD, Max has 23 papers published in high-impact peer reviewed journals since 2008, including 7 as 1st author, giving him an H-index of 11 and over 450 citations.
Max was awarded an ECR Visiting Fellowship by FSCIT to work with A/Prof Karayanidis’ group on model-based cognitive neuroscience analyses of cognitive flexibility and response inhibition in young adults.